Endocrine Abstracts

Pituitary stalk interruption syndrome (PSIS) is a rare clinical entity characterised by an absent or thin pituitary stalk, hypoplasia of the anterior pituitary gland, and ectopic location of the posterior pituitary on magnetic resonance imaging (MRI). Presentation is on early childhood or puberty and the most common hormonal deficiencies are growth hormone (GH) and gonadotropines. We present the case of a 28-year-old female patient who consulted after 2 years in secondary amen...

Introduction: The aim of this study was to analyze the effects of Liraglutide in hepatic steatosis as well as clinical and biochemical data before and after 6 months.Methods: We have retrospectively analysed epidemiological, anthropometric and laboratory data of 83 type 2 diabetic patients treated with Liraglutide and followed at different endocrinology units across east Andalusia. We have evaluated nonalcoholic fatty liver disease using liver enzymes an...

Objective: To characterise insulinoma diagnosed and treated in the period 1983–2014 in various hospitals in Spain.Methods: Inclusion criteria were the presence of biochemical and morphological criteria compatible with insulinoma and/or histologic demonstration of tumour.Results: Twenty-nine patients (23 women (79.3%); mean age 48.7±17.4 years (range, 16–74)) were recruited. In 26 (89.7%) cases the tumor was sporadic ...

Objective: To develop a specific questionnaire to evaluate the satisfaction of diabetic patients with the use of glucometers and evaluate their psychometric properties (feasibility, reliability, and validity).Material and methods: Two stages: i) questionnaire development: a set of 53 items was constructed after a bibliographic review. A panel of six experts and 50 patients concluded a 25-item version of the questionnaire (dimensions: satisfaction, inconv...

Introduction: In the geographical area of southern Spain, in the province of Huelva, we have detected prevalent cases of Dunnigan’s partial hereditary lipodystrophy. The genealogy, the suspicion phenotype and the coordination with the Genetics Service and Reference center, have borne fruit, and more and more families are detected in Our Area. The lipodystrophies, in general, are rare diseases that affect the adipose tissue, disappearance of it in different parts of the bo...

Objective: SGLT2 inhibitors, have been shown to improve glycaemic control, stabilize insulin dosing and mitigate insulin-associated weight gain in patients whose type 2 diabetes mellitus (T2DM) was inadequately controlled. The objective is to evaluate the real-world efficacy and safety of adding iSGLT-2 therapy in inadequately controlled patients with oral antidiabetic drugs and with or without insulin therapy.Materials and methods: This observational st...